32-4600); ATR (Cell Signaling Technology, Catalog No. despite increased replication stress, leading to apoptotic cell death in S-phase and mitotic catastrophe. These findings demonstrate that inhibition of BRD4 induces transcription-replication Deramciclane conflicts, DNA damage, and cell death in oncogenic cells. promoter in oncogenic cells, making it an attractive target in multiple models of cancer19,20. We … Continue reading 32-4600); ATR (Cell Signaling Technology, Catalog No